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Anti-BATF,堿性*拉鏈轉錄因子ATF樣(BATF)抗體說明書

閱讀:793發布時間:2012-10-13

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Rabbit Anti-BATF

Catalog Number : BYK-2988R       
Quantity size :   0.1ml (dilute with pH 7.4    0.01 M PBS or antibody diluent )
 
Background: B-ATF is a nuclear basic leucine zipper protein that belongs to the 
AP-1/ATF superfamily of transcription factors. The leucine zipper of B-ATF mediates 
dimerization with members of the Jun family of proteins. The B-ATF protein does not 
homodimerize efficiently, but rather forms a heterodimer preferentially with c-Jun. The 
B-ATF/c-Jun protein complex can interact with DNA containing a consensus binding 
site for AP-1, suggesting that B-ATF functions as a tissue-specific modulator of the 
AP-1 transcription complex in human cells. B-ATF also associates with IFP35, a 
leucine zipper protein that translocates to the nucleus following IFN treatment. The 
gene encoding B-ATF, also designated SFA-2, is strongly expressed in mature T and 
B lymphocytes, and is up-regulated after transformation by human T-cell leukemia 
virus type I. 
 
Specificity :   
        Anti-BATF is a rabbit monoclonal antibody unconjugated                
        specific for BATF of human, rat,mo          
        use for western blotting,elisa,immunoprecipitation and immunohistochemistry
        Protein G affinity chromatography purification, purity :>95%
        Isotype:  IgG
         mol wt:  86kDa
 
Application :  
        Western blotting 1:100-500                
         Immunohistochemistry 1:100-500                 
         ELISA 1:500-1000                  
         Optimal working dilutions must be determined by the end user.
 
Storage: Store at -20 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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