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Axiom Canine Genotyping Array Set A

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Axiom Canine Genotyping Array Set A

詳細介紹

Axiom™ Canine Genotyping Array Sets A and B were designed as part of the Expert Array Design program. The arrays offer access to approximately 1.1M markers that were discovered by the National Human Genome Research Institute of the National Institutes of Health. The content, distributed over two arrays, offers dense genotyping for validation and discovery of variants associated with specific phenotypes. All of the new content was discovered through high quality sequencing of over 300 dog genomes. The content on the array was aligned with the CanFam3 reference genome.

Canis Familiaris also serves as a model organism in understanding the human disease drug discovery process. Axiom canine genotyping arrays offer dense genotyping for isolating the variants associated with specific phenotypes. Understanding these genotypes allows breeders to anticipate the phenotypes of potential offspring, maximizing the potential to ensure dogs are mated with minimal inbreeding and to screen for possible genetic disorders.

Features of Axiom Canine Genotyping Array Set A
This array includes over 460,000 markers and includes legacy content from in-market arrays including new rare variants. The legacy content on the array offers the capability to continue your studies while getting access to new functional variants. The array includes:
• Markers from legacy in-market genotyping arrays
• Functional variants of biological relevance
• Intergenic variants based on newly available long non-coding RNA (lnc RNA) data
• miRNA variants
• Breed-specific markers

Learn more about Canine Array Set B ›

Applications of Axiom Canine Genotyping arrays
• Genome-wide association studies
• Veterinary research
• Direct-to-consumer applications
• As a model organism to help us understａnd complex human diseases such as cancer and diabetes

Data from the Axiom Canine Genotyping arrays are analyzed with Axiom Analysis Suite and Axiom CNV Summary Tools Software. Automated genotyping analysis with Axiom Analysis Software enables accurate genotyping of samples from various breeds including samples that exhibit in-breeding, a common occurrence in canine species.

For Research Use Only. Not for use in diagnostic procedures.