環(huán)保在線
詳細(xì)介紹
XBridge BEH C18 色譜柱被創(chuàng)造成為具有pH耐受能力的HPLC固定相商品。那些宣稱通過(guò)特殊表面修飾手段獲得高pH耐受力的色譜柱，根本無(wú)法與XBridge色譜柱的柱壽命表現(xiàn)相提并論，產(chǎn)品穩(wěn)定性與生俱來(lái)于BEH顆粒的合成工藝中。在加速pH10穩(wěn)定性測(cè)試條件下，將XBridge BEH C18柱與某些見(jiàn)的色譜柱以及那些號(hào)稱具有高pH穩(wěn)定性的色譜柱相比較，數(shù)據(jù)清楚表明，XBridge BEH C18柱超出其他色譜柱(XTerra)壽命10倍以上，色譜性能的降低微乎其微。
BEH C18 Batch-to-Batch Robustness for the Analysis of Rosuvastatin and Impurities
The main goal of this study is to investigate the long-term batch-to-batch reproducibility of 10 different lots of XBridge BEH C18 Columns.
When looking at the repeatability of chromatographic parameters using different batches of columns, variances may occur in retention times, peak symmetries, efficiencies, and various other parameters. Lot-to-lot reproducibility of the retention and several other profile characteristics of the peaks obtained with 10 columns from 10 different batches of XBridge BEH C18 will be examined in this work.
LC column batch-to-batch reproducibility is an example of a key control strategy to mitigate column performance risks and to further ensure good method performance throughout a method’s lifetime.
This application note also demonstrates the importance of robustness and control of the column temperature, the phase flow rate, and the phase composition obtained with the Waters equipment.
品名 | 編號(hào) |
XBridge BEH C18 Column, 130?, 3.5 µm, 3 mm X 150 mm, 1/pkg | 186003028 |
XBridge BEH C18 Column, 130?, 3.5 µm, 3 mm X 50 mm, 1/pkg | 186003026 |
XBridge BEH C18 Column, 130?, 3.5 µm, 3 mm X 100 mm, 1/pkg | 186003027 |
XBridge BEH C18 Column, 130?, 5 µm, 3 mm X 100 mm, 1/pkg | 186003132 |
XBridge BEH C18 Column, 130?, 3.5 µm, 4.6 mm X 250 mm, 1/pkg | 186003943 |
XBridge BEH C18 Column, 130?, 5 µm, 2.1 mm X 150 mm, 1/pkg | 186003110 |
XBridge BEH C18 Column, 130?, 3.5 µm, 3 mm X 30 mm, 1/pkg | 186003025 |
XBridge BEH C18 Column, 130?, 3.5 µm, 2.1 mm X 150 mm, 1/pkg | 186003023 |
XBridge BEH C18 Column, 130?, 3.5 µm, 2.1 mm X 100 mm, 1/pkg | 186003022 |
XBridge BEH C18 Column, 130?, 3.5 µm, 2.1 mm X 50 mm, 1/pkg | 186003021 |
XBridge BEH C18 Column, 130?, 3.5 µm, 2.1 mm X 30 mm, 1/pkg | 186003020 |
XBridge BEH C18 Column, 130?, 5 µm, 2.1 mm X 30 mm, 1/pkg | 186003129 |
XBridge BEH C18 Column, 130?, 5 µm, 2.1 mm X 100 mm, 1/pkg | 186003109 |
XBridge BEH C18 Column, 130?, 3.5 µm, 1 mm X 100 mm, 1/pkg | 186003127 |
XBridge BEH C18 Column, 130?, 3.5 µm, 1 mm X 150 mm, 1/pkg | 186003128 |
XBridge BEH C18 Column, 130?, 5 µm, 2.1 mm X 50 mm, 1/pkg | 186003108 |
XBridge BEH C18 Column, 130?, 3.5 µm, 1 mm X 50 mm, 1/pkg | 186003126 |
XBridge BEH C18 Column, 130?, 3.5 µm, 4.6 mm X 150 mm, 1/pkg | 186003034 |
XBridge BEH C18 Column, 130?, 3.5 µm, 4.6 mm X 100 mm, 1/pkg | 186003033 |
XBridge BEH C18 Column, 130?, 3.5 µm, 4.6 mm X 30 mm, 1/pkg | 186003030 |
XBridge BEH C18 Column, 130?, 3.5 µm, 4.6 mm X 75 mm, 1/pkg | 186003032 |
XBridge BEH C18 Column, 130?, 3.5 µm, 4.6 mm X 50 mm, 1/pkg | 186003031 |
XBridge BEH C18 Column, 130?, 5 µm, 4.6 mm X 75 mm, 1/pkg | 186003114 |
XBridge BEH C18 Column, 130?, 5 µm, 4.6 mm X 100 mm, 1/pkg | 186003115 |
XBridge BEH C18 Column, 130?, 5 µm, 4.6 mm X 150 mm, 1/pkg | 186003116 |
XBridge BEH C18 Direct Connect HP Column, 130?, 10 µm, 2.1 mm X 30 mm, 1/pkg | 186005232 |
XBridge BEH C18 Column, 130?, 5 µm, 4.6 mm X 250 mm, 1/pkg | 186003117 |
XBridge BEH C18 Column, 130?, 5 µm, 3 mm X 250 mm, 1/pkg | 186003133 |
XBridge BEH C18 Column, 130?, 5 µm, 4.6 mm X 30 mm, 1/pkg | 186003135 |
環(huán)保在線