PSCDBP抗體,產(chǎn)品報(bào)價(jià)胞粘蛋白結(jié)合調(diào)節(jié)蛋白抗體抗體應(yīng)用于WB、IHC、IF、ELISA等實(shí)驗(yàn)中，產(chǎn)品貨期快、質(zhì)量品牌保障，并提供完善的售前、售中、售后服務(wù)！咨詢(xún)或在線(xiàn)客服！我們將竭誠(chéng)為您服務(wù)！公司堅(jiān)持對(duì)產(chǎn)品質(zhì)量作不斷的評(píng)估、創(chuàng)新和改善以確保您對(duì)我們產(chǎn)品的高度信任！
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PSCDBP抗體,產(chǎn)品報(bào)價(jià)胞粘蛋白結(jié)合調(diào)節(jié)蛋白抗體產(chǎn)品介紹 CYTIP is a cytoplasmic protein that is involved in lymphocytic cell adhesion. Expressed primarily in hematopoetic cells, CYTIP regulates the activity of cytohesin-1 (an integrin-activating protein involved in cell adhesion) by mediating its recruitment to the leukocyte membrane. Through its ability to bind cytohesin-1, CYTIP is able to sequester it to the cytoplasm, thereby preventing cytohesin-1 translocation to lymphocytes and interrupting the flow of information in the cell adhesion pathway. CYTIP can be recruited from the cytoplasm to the membrane by leukocyte integrins which interact with CYTIP through its PDZ domain. After membrane translocation, CYTIP can be re-located to the cytoplasm via exposure to a phorbol ester. Additionally, CYTIP associates with SNX27 (sorting nexin 27) and helps to coordinate trafficking and signaling complexes. Up-regulation of CYTIP is observed in maturing dendritic cells, suggesting a possible role in developmentally-controlled cell adhesion.
胞粘蛋白結(jié)合調(diào)節(jié)蛋白抗體儲(chǔ)存溫度：存在于血清、組織培養(yǎng)上清液或腹水中的抗體在-20℃下能夠*儲(chǔ)存。低溫存放不會(huì)損傷抗體活性。抗體的工作液通常儲(chǔ)存于4℃中。此溫度下，抗體的活性能穩(wěn)定數(shù)月至數(shù)年亦不損失?？贵w溶液不應(yīng)反復(fù)凍融，因?yàn)榉磸?fù)凍融將導(dǎo)致部分抗體失活并產(chǎn)生不需要的蛋白—蛋白凝聚物?？贵w的凝聚能導(dǎo)致活性喪失。這是由于抗原結(jié)合位點(diǎn)的空間構(gòu)象被破壞，或由于產(chǎn)生的不溶物被離心或過(guò)濾而除去。冷凝蛋白類(lèi)的抗體不能存放于4℃。因?yàn)樵?℃下此類(lèi)抗體會(huì)發(fā)生沉淀。一些鼠源性IgG3亞類(lèi)的抗體有此特性。如果抗體在4℃下發(fā)生沉淀，就應(yīng)該存放于室溫下的疊氮鈉溶液中。
保存條件：低溫
運(yùn)輸：4度，或干冰。
公司抗體具有高純度、高效價(jià)、高特異性的特點(diǎn)，僅用于科學(xué)研究，不可用于臨床診斷及藥物治療，可以應(yīng)用于多種實(shí)驗(yàn)。

英文名稱(chēng) PSCDBP
抗體名稱(chēng)
別    名 CYTIP; B31; CASP; Cbp HE; CYBR; CYTHIP; Cytip; CYTIP_HUMAN; Cytohesin binder and regulator; Cytohesin-associated scaffolding protein; Cytohesin-binding protein HE; Cytohesin-interacting protein; HE antibody Pleckstrin Homology Sec7 and Coiled-Coil Domains Binding Protein; Pleckstrin homology Sec7 and coiled-coil domains-binding protein.  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞粘附分子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PSCDBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

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