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Anti-Mouse CD25 eFluor® 450 （Pacific Blue® replace

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產品型號25 ug

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更新時間：2017-08-01 02:04:31瀏覽次數：428次

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產品簡介

Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate eFluor 450
Laser Violet Laser
Emit 450 nm
Excite 405 nm
Reported Applications Flow Cytometric Analysis

詳細介紹

Description: The eBio3C7 antibody reacts with mouse CD25, the 55 kDa interleukin-2 receptor a chain （IL-2Ra）. CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 （IL-2 receptor beta chain） and CD132 （common γ chain） to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of the IL-2 receptor is inhibited by the 3C7 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody （typically PC61.5） and subsequent detection with another CD25 antibody.