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訪問次數(shù):1145更新時(shí)間:2017-07-12 16:50:22
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Description
Biochem/physiol Actions Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1.
Properties
assay ≥99% (TLC)
Gene Information human ... ALB(213), ALOX5(240), ELA2(1991), GPR44(11251), IL1A(3552), PLA2G1B(5319), PTGDR(5729), PTGS1(5742), PTGS2(5743)
rat ... Alox5(25290), Ptgs1(24693), Ptgs2(29527)
mouse ... Alox5(11689), Ptgdr(19214), Ptger1(19216), Ptger2(19217), Ptger3(19218), Ptger4(19219), Ptgs1(19224)
Safety
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes T+
Risk Statements 28
Safety Statements 28-36/37-45
RIDADR UN2811 6.1/PG 1
WGK Germany 3
RTECS NL3500000
References
reference Laneuville, O., et al., Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. J. Pharmacol. Exp. Ther. 271, 927-934, (1994)
Kato, M., et al., Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. J. Pharm. Pharmacol. 53, 1679-1685, (2001)
Merck Merck 13,4990
Beilstein Beil. 22,V,5,239
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