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產品簡介
Synonym: Monensin A sodium salt
CAS Number: 22373-78-0
Linear Formula: C36H61NaO11
Molecular Weight: 692.85
產品介紹
Description
Biochem/physiol Actions Na+ ionophore; blocks glycoprotein secretion; may induce catecholamine secretion from chromaffin cells. Useful in potentiometric and spectroscopic studies of alkali metal ion complexes.
Properties
assay 90-95% （TLC）
storage temp. 2-8°C
Safety
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 （EN 143） respirator cartridges
Hazard Codes T
Risk Statements 25
Safety Statements 36/37/39-45
RIDADR UN 3462 6.1/PG 2
WGK Germany 3
RTECS JH2830000
References
reference Callaway, T.R., et al., Selection of a highly monensin-resistant Prevola bryantii subpopulation with altered outer membrane characteristics. Appl. Environ. Microbiol. 65, 4753-4759, （1999） Abstract
Wang, X.D., et al., Phospholipase C activation by Na+/Ca2+ exchange is essential for monensin-induced Ca2+ influx and arachidonic acid release in FRTL-5 thyroid cells. J. Investig. Med. 47, 388-396, （1999） Abstract
Nebbia, C., et al., Oxidative metabolism of monensin in rat liver microsomes and interactions with tiamulin and other chemotherapeutic agents: evidence for the involvement of cytochrome P-450 3A subfamily. Drug Metab. Dispos. 27, 1039-1044, （1999） Abstract
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