PF 4 Human /人血小板因子-4（CXCL4）

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PF 4 Human /人血小板因子-4（CXCL4）產品編號：CHM-234
產品規格：5μg/20μg/1mg

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PF 4 Human /人血小板因子-4（CXCL4）

產品編號：CHM-234
產品規格：5μg/20μg/1mg

Synonyms	CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298.
Introduction	Plaet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated plaets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemokine family. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
Description	Human PF-4 a 7.8 kDa protein consisting of 70 amino acid residues.
Source	Human Plaets.
Physical Appearance	Sterile Filtered white lyophilized powder.
Formulation	The CXCL4 protein was lyophilized in PBS buffer.
Solubility	It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability	Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
Purity	Greater than 95.0% as determined by（a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE.
Amino acid sequence	The sequence of the first four N-terminal amino acids was determined and was found to be Glu-Ala-Glu-Glu.
Activity Control	Binding of HIT-antibodies.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY.They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals.