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Mouse Anti-COX-2 antibody
FROM:santa cruz
Catalog Number : RS-0732R
Quantity size :0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
background:
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Function:
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Specificity : Anti-COX-2 is a mouse monoclonal antibody.
specific for COX-2 antibody of Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep
– use for western blotting, elisa, immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt : 65kDa
Application :
Optimal working dilutions must be determined by the end user.
KLH conjugated synthetic peptide derived from human COX-2
Storage: Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
The lyophilized antibody is stable at room temperature for at least one month and for
greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M
PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃.
Important Note: This product as supplied is intended for research use only, not for
use in human, therapeutic or diagnostic applications.
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