產品編號 YB-2113R
英文名稱 Anti-F-AU5 tag抗體
中文名稱 AU5 tag標簽抗體
別 名 AU5 epitope tag; TDFYLK epitope tag; TDFYLK tag.
Anti-F-AU5 tag抗體
說 明 書 0.1ml 0.2ml
產品類型 標簽抗體
研究領域 細胞類型標志物
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 fusion protein,tagged T7 tag
產品應用 WB=1:100-500 ELISA=1:500-1000 ICC=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated to AU5 tag
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4
PubMed PubMed
產品介紹 background:
Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
上海鈺博生物科技有限公司是2012年5月由“海歸”組成的創業團隊與兩個專業投資機構發起成立的，以開發生產科研試劑和特色檢驗產品為方向，經過兩年多的努力，已經建立了免疫學和分子生物學的五個技術平臺，開發了ELISA/ELISpot酶聯免疫試劑盒、重組蛋白、熒光標記抗體、四聚體（Tetramer）特異性T細胞檢測試劑盒、Aimplex流式高通量多因子檢測、microRNA 表達譜分析和功能研究等系列產品和服務，研究論文在Nature、Eur. J. Immunol、The Journal of Immunology和Arthritis & Rheumatism等學術期刊上發表，與國內外免疫學、干細胞、傳染病和腫瘤研究及臨床檢驗領域的科學家們建立了良好的合作關系，形成了一定的品牌影響力。
鈺博生物另建有七大技術服務平臺（ELISA定制服務，免疫學檢測服務、分子生物學技術服務、蛋白表達與純化技術服務、抗體制備技術服務、細胞培養技術服務、整體實驗課題服務）并代理國外試劑：abcam 抗體；MBL，eBioscience，BD，R&D,Santan,CST,RayBiotech等品牌試劑，用專業的知識、專業的設備、專業的態度為客戶提供一站式實驗技術服務！
我們的優勢：完善、穩定的實驗體系，優秀的科研隊伍，實驗設備、準確可靠的實驗結果。稟存用戶*的原則，竭誠為您服務。質量是所有產品和服務關鍵的組成部分，我們通過質量和實力贏得客戶的信賴。產品的質量是企業的生命。
Elisa試劑盒，檢測試劑盒，抗體，生化試劑，微生物培養基，重組蛋白，血清，實驗耗材等產品
Anti-F-AU5 tag抗體 產品信息
