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當(dāng)前位置:廈門慧嘉生物科技有限公司>>細(xì)胞因子>>Prospec >>IGFBP 5 Human/ 人胰島素樣生長(zhǎng)因子結(jié)合蛋白-5 產(chǎn)品編號(hào):CYT-464

IGFBP 5 Human/ 人胰島素樣生長(zhǎng)因子結(jié)合蛋白-5 產(chǎn)品編號(hào):CYT-464

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IGFBP 5 Human/ 人胰島素樣生長(zhǎng)因子結(jié)合蛋白-5 產(chǎn)品編號(hào):CYT-464
產(chǎn)品規(guī)格:5μg/25μg/1mg

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IGFBP 5 Human/ 人胰島素樣生長(zhǎng)因子結(jié)合蛋白-5

產(chǎn)品編號(hào):CYT-464
產(chǎn)品規(guī)格:5μg/25μg/1mg
 

Synonyms IGFBP-5, IBP-5, IGF-binding protein 5.
Introduction IGFBP5 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Description IGFBP5 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 253 amino acids and having a molecular mass of 28613 Dalton.
IGFBP5 is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation IBP-5 was lyophilized from a concentrated (1mg/ml) solution containing 10mM sodium Citrate PH 3.0.
Solubility It is recommended to reconstitute the lyophilized Insulin-like Growth Factor Binding Protein-5 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized IBP5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGFBP 5 should be stored at 4°C between 2-7 days and for future use below
-18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity Greater than 98.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Amino acid sequence The sequence of the first five N-terminal amino acids was determined and was found to be Met-Leu-Gly-Ser-Phe.
Biological Activity The ED50, calculated by its ability to inhibit IGF-II induced proliferation of MCF-7 is < 0.3 μg/ml in the presence of 15 ng/ml of Human IGF-II.
Usage ProsSec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals.


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